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제목 Dosimetry in radionuclide therapy: position for students and postdocs 공고
작성자 : 관리자 등록일 : 2022-06-08 조회수 :360
작성자 관리자 등록일 2022-06-08 조회수 360
첨부파일 첨부파일 :
We have an open position for a postdoctoral fellow and/or students* of physics, medical physics, nuclear/mechanical engineering, and computer science interested in developing new methods to compute and assess the radiation dosimetry in the novel radionuclide therapies in cancer care. Our team is within the Physics Division at the Massachusetts General Hospital, Department of Radiation Oncology(https://paganetti-lab.mgh.harvard.edu).
 
Project background: Radionuclide therapy (RNT) consists of the administration of radioactive sources in a selective way so that tumor cells take up considerably more radioactivity than healthy cells. As tumor cells are targeted by means of ionizing radiation, the clinical outcome is expected to be driven by radiation dose. However, dosimetry methods largely need to be developed and/or refined.
 
Project overview: This project focuses on the use of microspheres labeled with the beta-emitter Y90. In clinical practice, microspheres are injected in the proximities of liver tumors, so they get lodged in the surrounding vessels, which is known as radioembolization. The therapeutic effect is achieved through the beta particles emitted by the Y90-labeled microspheres. We will work on new methods to determine dosimetry in Y90-microsphere treatments. Our specific aims are:
  • Use of liver-specific vasculature computational models to study the flow of microspheres once injected into the liver.
  • Study of the influence of different parameters of the administration of Y90 in the liver dose distribution
 
Besides the main project, the candidate will have the opportunity to work on other projects conducted within our team, such as Monte Carlo applications, radiobiological modeling, or RBE in proton radiotherapy.
MGH is an equal opportunity employer. We value diversity highly and encourage international and minority candidates to apply.
 
*Students: Our team cannot host an education program as the main institution. Students hosted by other institutions are invited to apply and their salary will be supported by our team.
To apply: Email your CV and letters of reference to Alejandro Bertolet, PhD (abertoletreina@mgh.harvard.edu) and/or Harald Paganetti, PhD (hpaganetti@mgh.harvard.edu)
 
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